N Wald 2018: Public health failure in the prevention of neural tube defects: time to abandon the tol

N Wald 2018: Public health failure in the prevention of neural tube defects: time to abandon the tol 2018

"There is no scientific basis for setting an upper level of intake for folate. Having such a

limit, which has been set at 1 mg per day, has acted as a barrier to the wider introduction

of mandatory fortification of flour with folic acid to prevent neural tube defects.

For both reasons, the upper limit should be discarded. This would have the practical

effect of leaving no scientific obstacle to the introduction of mandatory folic acid fortification

in all countries, which would have an important global impact on the prevention of neural tube defects.”
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